Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092992 | 0.84 | TRPV4 (0.36) | TRPV4IDO1ESR1ESR2 | |
| SCHEMBL28943097 | 0.79 | ALDH1A1 (0.46) | IDO1 | |
| SCHEMBL673282 | 0.76 | LMNA (0.43) | ESR1ESR2 | |
| SCHEMBL19523009 | 0.75 | TSHR (0.48) | TRPV4IDO1ESR1ESR2 | |
| SCHEMBL1119510 | 0.75 | ESR1 (0.31) | ESR1ESR2 | |
| SCHEMBL5068336 | 0.75 | ESR1 (0.58) | ESR1ESR2 | |
| SCHEMBL14577302 | 0.75 | CA1 (0.43) | ESR1ESR2 | |
| SCHEMBL14576987 | 0.75 | TRPV1 (0.36) | ESR1ESR2 | |
| SCHEMBL18242205 | 0.75 | PGK1 (0.31) | ESR1ESR2 | |
| SCHEMBL8176042 | 0.75 | KIF11 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254578-A | Cardiovascular disorders | SANKYO COMPANY, LIMITED (JP) | 1993-10-19 | — | — | US | disclosed |
| US-5247022-A | Housings, automobiles; heat resistance, stability | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-21 | — | — | US | disclosed |
| EP-0482931-A1 | Benzopyran derivatives having anti-hypertensive and vasodilatory activity, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1992-04-29 | — | — | EP | disclosed |