Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941647 | 0.80 | CYP1A2 (0.46) | MAOAMAOBCYP3A4CYP1A2HIF1A | |
| SCHEMBL971097 | 0.79 | APP (0.53) | HSD17B10MAOAMAOBRAB9ANPC1 | |
| SCHEMBL11159851 | 0.75 | CYP1A2 (0.60) | HSD17B10MAOAMAOBRAB9ASLC6A4 | |
| SCHEMBL9216740 | 0.73 | DDAH1 (0.41) | HSD17B10MAOAMAOBSLC6A4SMN1; SMN2 | |
| SCHEMBL9481328 | 0.71 | HSD17B10 (0.43) | HSD17B10MAOAMAOBRAB9ASLC6A4 | |
| SCHEMBL332623 | 0.71 | MAOA (0.63) | HSD17B10MAOAMAOBRAB9ASLC6A4 | |
| SCHEMBL442875 | 0.70 | MAOA (0.49) | HSD17B10MAOAMAOBRAB9ASLC6A4 | |
| SCHEMBL7015159 | 0.69 | CALM1 (0.50) | LMNACYP1A2 | |
| SCHEMBL28084553 | 0.69 | MAOA (0.61) | HSD17B10MAOAMAOBRAB9ASLC6A4 | |
| SCHEMBL4366554 | 0.69 | MEN1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247381-B1 | 5-FLUROROURACIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| EP-0247381-A2 | 5-flurorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |