Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664933 | 0.80 | APP (0.54) | MAOAMAOBMEN1KMT2ADAO | |
| SCHEMBL332623 | 0.79 | MAOA (0.63) | MAOAMAOBPOLBHSD17B10SLC6A4 | |
| SCHEMBL402875 | 0.78 | MAOA (0.58) | MAOAMAOBPOLBHSD17B10SLC6A4 | |
| SCHEMBL1712262 | 0.78 | MAOA (0.53) | MAOAMAOBPOLBHSD17B10SLC6A4 | |
| SCHEMBL28084553 | 0.77 | MAOA (0.61) | MAOAMAOBPOLBHSD17B10SLC6A4 | |
| SCHEMBL6662388 | 0.76 | CA12 (0.41) | KMT2ANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL21981583 | 0.74 | BRD4 (0.32) | HSD17B10NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10055053 | 0.74 | ALDH1A1 (0.57) | MAOAMAOBPOLBHSD17B10SLC6A4 | |
| SCHEMBL3612916 | 0.74 | — | — | |
| SCHEMBL972188 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112258-A1 | SEROTONIN RECEPTOR AS A TARGET FOR THERAPY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2024-05-30 | — | — | WO | claimed |
| CN-116323558-A | Compounds and methods for treating diseases | 艾特里提治疗有限公司 | 2023-06-23 | — | — | CN | claimed |
| US-11603364-B2 | Acyl hydrazone derivative compounds for treating disease | Alterity Therapeutics Limited (AU) | 2023-03-14 | — | — | US | claimed |
| CN-114920753-A | 6-fluoro-dihydropyrano [2,3-c ] pyrazole derivative and synthetic method and application thereof | 华南理工大学 | 2022-08-19 | — | — | CN | claimed |
| US-20220169676-A1 | INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES | WASHINGTON UNIVERSITY (US) | 2022-06-02 | — | — | US | claimed |
| EP-3989997-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS | Washington University (US) | 2022-05-04 | — | — | EP | claimed |
| US-20220073461-A1 | (2,5-DIOXOPYRROLIDIN-1-YL)(PHENYL)-ACETAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | WARSZAWSKI UNIWERSYTET MEDYCZNY (PL) | 2022-03-10 | — | — | US | claimed |
| EP-3908580-A1 | (2,5-DIOXOPYRROLIDIN-1-YL)(PHENYL)-ACETAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | UNIWERSYTET JAGIELLONSKI (PL) | 2021-11-17 | — | — | EP | claimed |
| WO-2020264187-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS | JANETKA JAMES (US) | 2020-12-30 | — | — | WO | claimed |
| WO-2020145831-A1 | (2,5-DIOXOPYRROLIDIN-L-YL)(PHENYL)-ACETAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | Uniwersytet Jagielloński (PL) | 2020-07-16 | — | — | WO | claimed |
| EP-0593559-A1 | AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LTD. (GB) | 1994-04-27 | — | — | EP | claimed |
| EP-0587377-A2 | Thiazolidinone derivatives as hypoglycemic agents and for treating Alzheimer's disease | ELI LILLY AND COMPANY (US) | 1994-03-16 | — | — | EP | claimed |
| WO-1994001402-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS TACHYKININ DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1994-01-20 | — | — | WO | claimed |
| WO-1993001169-A2 | AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LIMITED (GB) | 1993-01-21 | — | — | WO | claimed |
| US-4891383-A | Derivatives of 5-pentylamino-5-oxopentanoic and 4-pentylamino-4-oxobutanoic acids with antagonistic activity towards cholecystokinin and a method for their preparation | ROTTA RESEARCH LABORARORIUM S.P.A. (IT) | 1990-01-02 | — | — | US | claimed |
| EP-0126311-B1 | BENZOPYRAN DERIVATIVES. | BEECHAM GROUP PLC (GB) | 1989-09-13 | — | — | EP | claimed |
| US-4616002-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-10-07 | — | — | US | claimed |
| US-4571406-A | Anti-hypertensive chromans and chromenes | BEECHAM GROUP P.L.C. (GB) | 1986-02-18 | — | — | US | claimed |
| EP-0145956-A1 | Composés amidés | CIBA-GEIGY AG (CH) | 1985-06-26 | — | — | EP | claimed |
| EP-0126311-A2 | Benzopyran derivatives. | BEECHAM GROUP PLC (GB) | 1984-11-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11603364-B2 | Acyl hydrazone derivative compounds for treating disease | FH, ACOX1, HDAC1 | MAOA 532/4885MAOB 564/4885POLB 2517/4885 |
| US-20220073461-A1 | (2,5-DIOXOPYRROLIDIN-1-YL)(PHENYL)-ACETAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | TRPV5, P2RX5, TRPV1 | MAOA 301/4885MAOB 519/4885POLB 3803/4885 |
| US-20220169676-A1 | INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES | HDGF, MMP7, HGF | MAOA 362/4885MAOB 747/4885POLB 3087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.