Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14383870 | 0.84 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL27993116 | 0.83 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL17325503 | 0.83 | ADRA1D (0.53) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL23302280 | 0.83 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL23302378 | 0.81 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9793625 | 0.80 | S100A4 (0.41) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL19601473 | 0.79 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL24125024 | 0.78 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL22169133 | 0.78 | ALDH1A1 (0.44) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL31231922 | 0.75 | ALDH1A1 (0.50) | ADRA1DADRA1AADRA1BHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456152-B1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | SASOL TECH PTY LTD (ZA) | 2012-06-13 | — | — | EP | claimed |
| JP-4308015-B2 | — | — | 2009-08-05 | — | — | JP | claimed |
| US-7300904-B2 | Trimerisation and oligomerisation of olefins using a chromium based catalyst | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2007-11-27 | — | — | US | claimed |
| JP-2005533872-A | — | — | 2005-11-10 | — | — | JP | claimed |
| US-20050131262-A1 | Trimerisation and oligomerisation of olefins using a chromium based catalyst | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2005-06-16 | — | — | US | claimed |
| EP-1456152-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | Sasol Technology (Pty) Ltd (ZA) | 2004-09-15 | — | — | EP | claimed |
| WO-2003053890-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | SASOL TECHNOLOGY (PTY) LTD (ZA) | 2003-07-03 | — | — | WO | claimed |
| EP-2287144-B1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2018-04-11 | — | — | EP | disclosed |
| EP-2287143-B1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2018-04-11 | — | — | EP | disclosed |
| US-20170044275-A9 | Methods of Preparation of an Olefin Oligomerization Catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2017-02-16 | — | — | US | disclosed |
| US-9550841-B2 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160251455-A1 | Methods of Preparation of an Olefin Oligomerization Catalyst | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2016-09-01 | — | — | US | disclosed |
| EP-1716089-B1 | METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST | CHEVRON PHILLIPS CHEMICAL CO (US) | 2015-04-08 | — | — | EP | disclosed |
| EP-1716089-A1 | METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST | Chevron Phillips Chemical Company LP (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005082816-A1 | METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2005-09-09 | — | — | WO | disclosed |
| US-20050187391-A1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2005-08-25 | — | — | US | disclosed |
| US-20050187098-A1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY, LP | 2005-08-25 | — | — | US | disclosed |
| US-20050131262-A1 | Trimerisation and oligomerisation of olefins using a chromium based catalyst | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2005-06-16 | — | — | US | disclosed |
| EP-1456152-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | Sasol Technology (Pty) Ltd (ZA) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053890-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | SASOL TECHNOLOGY (PTY) LTD (ZA) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187391-A1 | Methods of preparation of an olefin oligomerization catalyst | ZRANB2, COG4, PPOX | ADRA2A 4041/4885ADRA2B 3946/4885ADRA2C 3570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.