Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | WRN | Q14191 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24726775 | 0.80 | AKT1 (0.45) | LMNAALDH1A1AKT1MAPK1HTT | |
| SCHEMBL18973738 | 0.80 | AKT1 (0.40) | LMNAALDH1A1AKT1MAPK1HTT | |
| SCHEMBL23432931 | 0.76 | PGA5 (0.36) | AKT1 | |
| SCHEMBL16307668 | 0.76 | SMN1; SMN2 (0.49) | LMNAALDH1A1AKT1MAPK1HTT | |
| SCHEMBL24024229 | 0.76 | OPRM1 (0.35) | LMNAALDH1A1AKT1OPRM1OPRD1 | |
| SCHEMBL12286466 | 0.76 | MGLL (0.43) | LMNAALDH1A1AKT1MAPK1HTT | |
| SCHEMBL16731691 | 0.76 | AKT1 (0.47) | LMNAALDH1A1AKT1MAPK1HTT | |
| SCHEMBL21648873 | 0.75 | MGLL (0.51) | LMNAALDH1A1AKT1HTTSMN1; SMN2 | |
| SCHEMBL998261 | 0.75 | AKT1 (0.59) | ALDH1A1AKT1MEN1KMT2ATDP1 | |
| SCHEMBL20574342 | 0.74 | AKT1 (0.53) | ALDH1A1AKT1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180816-A | One vial method for labeling protein/linker conjugates with technetium-99M | CENTOCOR (US) | 1993-01-19 | — | — | US | disclosed |
| US-5144043-A | Coupling protein or peptide to radionucleotide; labeling antibodies | CENTOCOR (US) | 1992-09-01 | — | — | US | disclosed |