SCHEMBL9486648

SCHEMBL9486648

CCc1nc(-c2cccc(C)c2O)nc(-c2cccc(C)c2O)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
TRPA1 O75762 1/20 0.39
F2 P00734 1/20 0.37
F10 P00742 1/20 0.37
PLG P00747 1/20 0.37
PLAU P00749 1/20 0.37
PLAT P00750 1/20 0.37
PRSS1 P07477 1/20 0.37
LMNA P02545 2/20 0.37
TSHR P16473 1/20 0.37
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
GAA P10253 4/20 0.35
MGAM O43451 2/20 0.35
SI P14410 2/20 0.35
MGAM2 Q2M2H8 2/20 0.35
HSD17B10 Q99714 3/20 0.34
KDM4E B2RXH2 3/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12714311 0.87 ALDH1A1 (0.56) ALDH1A1TRPA1F2F10PLG
SCHEMBL22100520 0.77 L3MBTL1 (0.52) ALDH1A1TRPA1LMNATSHRGAA
SCHEMBL9637931 0.77 MAPK1 (0.58) ALDH1A1LMNATSHRGAAHSD17B10
SCHEMBL18780272 0.76 ALDH1A1 (0.43) ALDH1A1TRPA1F2F10PLG
SCHEMBL28968048 0.74 GABRA1 (0.61) GABRA1GABRB2GAAMAPK1MAPT
SCHEMBL30117290 0.74 GABRA1 (0.61) GABRA1GABRB2GAAMAPK1MAPT
SCHEMBL2210594 0.72 ALDH1A1 (0.72) ALDH1A1TRPA1F2F10PLG
SCHEMBL30688234 0.72 ALDH1A1 (0.72) ALDH1A1TRPA1F2F10PLG
SCHEMBL6209944 0.71 MAPT (0.39) ALDH1A1TRPA1LMNATSHRHSD17B10
SCHEMBL6509217 0.71 NR1H4 (0.49) ALDH1A1LMNAHSD17B10KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0245204-B1 PROCESS FOR THE PHOTOCHEMICAL STABILIZATION OF UNDYED AND DYED FIBROUS POLYAMIDE MATERIAL AND ITS MIXTURE WITH OTHER FIBRES CIBA-GEIGY AG (CH) 1993-08-04 EP disclosed
US-5221287-A Blend with polypropylene or polyurethane and hindered amine light stabilizer CIBA-GEIGY CORPORATION (US) 1993-06-22 US disclosed
EP-0409771-A2 Process of photochemical and thermal stabilization of polyamide fibres, dyeable by acid and basic dyes, and of their mixtures amongst themselves and with other fibres CIBA-GEIGY AG (CH) 1991-01-23 EP disclosed
US-4874391-A USING WATER SOLUBLE COPPER COMPLEX AZO DYE, LIGHT STABILIZER AND ANTIOXIDANT CIBA-GEIGY CORPORATION (US) 1989-10-17 US disclosed
US-4775386-A Process for photochemical stabilization of undyed and dyed polyamide fibre material and blends thereof with other fibres: copper complex and light stabilizer treatment CIBA-GEIGY CORPORATION (US) 1988-10-04 US disclosed
EP-0255481-A1 Process for the photochemical stabilisation of a fibrous polyamide material and its mixtures with other fibres CIBA-GEIGY AG (CH) 1988-02-03 EP disclosed
EP-0245204-A1 Process for the photochemical stabilization of undyed and dyed fibrous polyamide material and its mixture with other fibres CIBA-GEIGY AG (CH) 1987-11-11 EP disclosed