Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12714311 | 0.89 | ALDH1A1 (0.56) | ALDH1A1TRPA1MAPK1KMT2AGAA | |
| SCHEMBL18780272 | 0.88 | ALDH1A1 (0.43) | L3MBTL1TSHRADORA2AALOX15ADORA3 | |
| SCHEMBL12228467 | 0.85 | EGFR (0.51) | L3MBTL1TSHRALDH1A1MAPK1MEN1 | |
| SCHEMBL17993428 | 0.83 | L3MBTL1 (0.61) | L3MBTL1TSHRADORA2AALOX15ADORA3 | |
| SCHEMBL6509217 | 0.82 | NR1H4 (0.49) | ALDH1A1MEN1KMT2ACYP1A2CLK4 | |
| SCHEMBL25107058 | 0.81 | L3MBTL1 (0.55) | L3MBTL1TSHRADORA2AALOX15ADORA3 | |
| SCHEMBL5710676 | 0.81 | ADORA2A (0.64) | L3MBTL1TSHRADORA2AALOX15ADORA3 | |
| SCHEMBL19088146 | 0.81 | ALDH1A1 (0.37) | L3MBTL1TSHRADORA2AALOX15ADORA3 | |
| SCHEMBL12202811 | 0.81 | TSHR (0.68) | L3MBTL1TSHRADORA2AALOX15ADORA3 | |
| SCHEMBL581901 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TRPA1KMT2AHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017474-A1 | Novel Polycyclic Compound | EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) | 2022-01-20 | — | — | US | disclosed |
| EP-3896067-A1 | NOVEL POLYCYCLIC COMPOUND | Eutec New Materials Technology (Suzhou) Co., Ltd (CN) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020118933-A1 | NOVEL POLYCYCLIC COMPOUND | 优缔新材料科技(苏州)有限公司 | 2020-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017474-A1 | Novel Polycyclic Compound | CUTA, DSG1, UACA | L3MBTL1 949/4885TSHR 2166/4885ADORA2A 4606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.