Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202613 | 0.74 | TSHR (0.46) | TSHRLMNAALDH1A1F2ADRB2 | |
| SCHEMBL27286616 | 0.74 | ALDH1A1 (0.61) | TSHRLMNAALDH1A1ADRB2ADRB1 | |
| SCHEMBL21603078 | 0.73 | TSHR (0.52) | TSHRLMNAALDH1A1F2ADRB2 | |
| SCHEMBL203317 | 0.70 | TSHR (0.58) | TSHRLMNAALDH1A1F2POLB | |
| SCHEMBL1759366 | 0.70 | TSHR (0.58) | TSHRLMNAALDH1A1F2POLB | |
| SCHEMBL7070049 | 0.70 | TSHR (0.58) | TSHRLMNAALDH1A1F2POLB | |
| SCHEMBL7285241 | 0.70 | LMNA (0.54) | TSHRLMNAALDH1A1F2ADRB2 | |
| SCHEMBL9127213 | 0.70 | LMNA (0.50) | TSHRLMNAF2TDP1TP53 | |
| SCHEMBL10911268 | 0.70 | TSHR (0.44) | TSHRLMNAALDH1A1F2TDP1 | |
| SCHEMBL27879469 | 0.70 | ADRB2 (0.48) | TSHRLMNAALDH1A1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232199-B1 | AROMATIC BENZAMIDO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AS WELL AS IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-02-03 | — | — | EP | disclosed |
| EP-0232199-A2 | Aromatic benzamido compounds, process for their preparation and their use in human or veterinary medicine as well as in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1987-08-12 | — | — | EP | disclosed |