SCHEMBL3880437

SCHEMBL3880437

N#Cc1cc(-c2ccccc2)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.57
MAOA P21397 2/20 0.56
MAOB P27338 2/20 0.56
XDH P47989 1/20 0.53
ALDH1A1 P00352 6/20 0.52
KDM4E B2RXH2 4/20 0.52
HPGD P15428 2/20 0.52
LMNA P02545 2/20 0.52
GAA P10253 2/20 0.52
HTT P42858 2/20 0.52
ESR2 Q92731 2/20 0.52
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
HSP90AA1 P07900 1/20 0.52
MAPT P10636 1/20 0.52
ALOX15 P16050 1/20 0.52
ALOX12 P18054 1/20 0.52
KMT2A Q03164 1/20 0.52
HSD17B10 Q99714 1/20 0.52
MCL1 Q07820 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24055427 0.96 MAOA (0.54) ALOX5MAOAMAOBXDHALDH1A1
SCHEMBL30787959 0.96 MAOA (0.54) ALOX5MAOAMAOBXDHALDH1A1
SCHEMBL3320621 0.84 ALOX5 (0.57) ALOX5MAOAMAOBXDHALDH1A1
SCHEMBL8264987 0.82 AR (0.56) MAOAMAOBXDHESR2HDAC8
SCHEMBL769249 0.81 ALDH1A1 (0.62) MAOAMAOBALDH1A1KDM4EHPGD
SCHEMBL14566193 0.81 QDPR (0.60) XDHLMNAESR2MAPTCYP11B1
SCHEMBL948906 0.80 ALOX5 (0.57) ALOX5MAOAMAOBALDH1A1KDM4E
Hydrochloric Acid SCHEMBL5307083 0.79 QDPR (0.58) XDHLMNAESR2MAPTCYP11B1
SCHEMBL16158538 0.78 USP7 (0.46) MAOAMAOBXDHESR2MCL1
SCHEMBL28676109 0.78 TRIM24 (0.50) MAOAMAOBXDHALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12252496-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2025-03-18 US disclosed
US-20210206775-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-07-08 US disclosed
US-20210206775-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-07-08 US disclosed
CN-112218870-A Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2021-01-12 CN disclosed
EP-2764866-A1 Inhibitors of nedd8-activating enzyme IP Gesellschaft für Management mbH (DE) 2014-08-13 EP disclosed
WO-2013021309-A1 INTERMEDIATE AND PROCESS FOR THE PREPARATION OF A SULFONAMIDE DERIVATIVE PFIZER LIMITED (GB) 2013-02-14 WO disclosed
EP-2010485-A1 AZETIDINE DERIVATIVES AS G-PROTEIN COUPLED RECEPTOR (GPR119 ) AGONISTS Prosidion Limited (GB) 2009-01-07 EP disclosed
WO-2007116230-A1 AZETIDINE DERIVATIVES AS G-PROTEIN COUPLED RECEPTOR (GPR119 ) AGONISTS PROSIDION LTD (GB) 2007-10-18 WO disclosed
WO-2007025575-A1 O-HYDROXY- AND O-AMINO BENZAMIDE DERIVATIVES AS IKK2 INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2007-03-08 WO disclosed
CN-1208403-A Compounds BRITISH ASTRA PHARMACEUTICALS (GB) 1999-02-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12252496-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device TPMT, POU5F1, CCND1 ALOX5 359/4885MAOA 940/4885MAOB 749/4885
US-20210206775-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device TPMT, POU5F1, CCND1 ALOX5 359/4885MAOA 940/4885MAOB 749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.