Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | MMP7 | P09237 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP12 | P39900 | 3/20 | 0.48 |
| ▸ | MMP14 | P50281 | 3/20 | 0.48 |
| ▸ | MMP15 | P51511 | 3/20 | 0.48 |
| ▸ | MMP16 | P51512 | 3/20 | 0.48 |
| ▸ | MMP26 | Q9NRE1 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490586 | 0.93 | FFAR1 (0.51) | GHSRGRIN1GRIN2BFFAR1MMP1 | |
| SCHEMBL9215265 | 0.89 | LIPG (0.49) | GRIN1GRIN2BFFAR1LIPG | |
| SCHEMBL9493490 | 0.84 | NPC1 (0.47) | ALOX5PTGS1PTGS2MAOB | |
| SCHEMBL9200460 | 0.83 | PPARD (0.43) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9491752 | 0.83 | FFAR1 (0.46) | FFAR1ALOX5 | |
| SCHEMBL9488819 | 0.82 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL9597603 | 0.80 | MTNR1A (0.47) | — | |
| SCHEMBL9488175 | 0.80 | PPARD (0.47) | FFAR1MMP1MMP2MMP7MMP9 | |
| SCHEMBL9534252 | 0.78 | PPARD (0.51) | ALOX5MAOB | |
| SCHEMBL9215988 | 0.78 | MAOB (0.46) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256789-A | Antiinflammatory hydroxamic acids and N-hydroxyureas | PFIZER INC. (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991016298-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS | PFIZER INC (US) | 1991-10-31 | — | — | WO | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |