Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215265 | 0.89 | LIPG (0.49) | — | |
| SCHEMBL9488819 | 0.83 | FFAR1 (0.51) | — | |
| SCHEMBL9203514 | 0.82 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9223074 | 0.79 | SCN3A (0.64) | MAOB | |
| SCHEMBL9597113 | 0.79 | PPARD (0.46) | PPARD | |
| SCHEMBL9216479 | 0.79 | MAOB (0.54) | MAOB | |
| SCHEMBL9213857 | 0.78 | SCN3A (0.51) | — | |
| SCHEMBL9215988 | 0.78 | MAOB (0.46) | MAOAMAOB | |
| SCHEMBL9488175 | 0.78 | PPARD (0.47) | PPARDMAOB | |
| SCHEMBL9490580 | 0.78 | GHSR (0.50) | ALOX5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256789-A | Antiinflammatory hydroxamic acids and N-hydroxyureas | PFIZER INC. (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0525111-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS. | PFIZER (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991016298-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS | PFIZER INC (US) | 1991-10-31 | — | — | WO | disclosed |