Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203514 | 0.88 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9597603 | 0.84 | MTNR1A (0.47) | PPARD | |
| SCHEMBL9490580 | 0.83 | GHSR (0.50) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9597113 | 0.82 | PPARD (0.46) | PPARD | |
| SCHEMBL9490649 | 0.81 | P2RX3 (0.49) | P2RX3P2RX2 | |
| SCHEMBL9597741 | 0.80 | PPARD (0.47) | PPARD | |
| SCHEMBL9596948 | 0.80 | PPARD (0.47) | PPARDALOX5 | |
| SCHEMBL9597410 | 0.79 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9597206 | 0.79 | PPARD (0.43) | PPARD | |
| SCHEMBL9201774 | 0.78 | MAOA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525111-B1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS | PFIZER (US) | 1995-06-14 | — | — | EP | claimed |
| US-5256789-A | Antiinflammatory hydroxamic acids and N-hydroxyureas | PFIZER INC. (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0525111-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS. | PFIZER (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991016298-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS | PFIZER INC (US) | 1991-10-31 | — | — | WO | disclosed |