Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490586 | 0.91 | FFAR1 (0.51) | NPC1POLBRAB9AGFERPAX8 | |
| SCHEMBL9491758 | 0.89 | MAOA (0.47) | MAOAMAOBTAOK1 | |
| SCHEMBL9490580 | 0.84 | GHSR (0.50) | MAOBALOX5PTGS1PTGS2 | |
| SCHEMBL9491752 | 0.81 | FFAR1 (0.46) | NPC1POLBRAB9AGFERPAX8 | |
| SCHEMBL9488819 | 0.80 | FFAR1 (0.51) | — | |
| SCHEMBL1843521 | 0.79 | FABP4 (0.53) | NPC1POLBRAB9AGFERPAX8 | |
| SCHEMBL13198517 | 0.78 | MAOA (0.53) | MAOAMAOBALOX5 | |
| SCHEMBL9490252 | 0.76 | HTT (0.58) | RAB9A | |
| SCHEMBL3750778 | 0.75 | FFAR1 (0.53) | MAOAMAOB | |
| SCHEMBL3412786 | 0.75 | FFAR1 (0.53) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |