Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854159 | 0.79 | PGR (0.44) | SMN1; SMN2NPSR1MAPTLMNAATM | |
| SCHEMBL20267879 | 0.75 | SMN1; SMN2 (0.35) | SMN1; SMN2NPSR1MAPTLMNAATM | |
| SCHEMBL7370238 | 0.70 | SMN1; SMN2 (0.43) | SMN1; SMN2NPSR1MAPTLMNAATM | |
| SCHEMBL3244408 | 0.70 | NPSR1 (0.43) | SMN1; SMN2NPSR1MAPTLMNAATM | |
| SCHEMBL28158669 | 0.70 | SMN1; SMN2 (0.43) | SMN1; SMN2NPSR1MAPTLMNAATM | |
| SCHEMBL8017607 | 0.69 | CES2 (0.44) | SMN1; SMN2NPSR1MAPTLMNAATM | |
| SCHEMBL4815873 | 0.67 | SMN1; SMN2 (0.41) | SMN1; SMN2NPSR1MAPTLMNAATM | |
| SCHEMBL29028319 | 0.67 | SMN1; SMN2 (0.36) | SMN1; SMN2NPSR1MAPTLMNAATM | |
| SCHEMBL5664608 | 0.67 | ALDH1A1 (0.46) | SMN1; SMN2NPSR1MAPTLMNAATM | |
| SCHEMBL693987 | 0.67 | SMN1; SMN2 (0.50) | SMN1; SMN2NPSR1MAPTLMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180799-A | Organolithium-Organoaluminum Catalyst | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-19 | — | — | US | disclosed |
| EP-0434316-A1 | Processes | ZENECA LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |