Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MMP15 | P51511 | 1/20 | 0.46 |
| ▸ | MMP16 | P51512 | 1/20 | 0.46 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488534 | 0.93 | SMPD1 (0.48) | SPHK2SMPD1MMP1MMP2MMP7 | |
| SCHEMBL9490621 | 0.88 | MAOB (0.52) | ALDH1A1TAS1R3TAS1R1TAS1R2SPHK2 | |
| SCHEMBL9487573 | 0.88 | TAOK1 (0.53) | MMP1MMP2MMP7MMP9MMP12 | |
| SCHEMBL9490515 | 0.86 | TAS1R3 (0.56) | ALDH1A1TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL9492340 | 0.84 | GAA (0.48) | ALDH1A1SCN3ATAOK1MAPT | |
| SCHEMBL9488808 | 0.80 | LIPG (0.57) | MMP1MMP2MMP7MMP9MMP12 | |
| SCHEMBL22289691 | 0.80 | ADRA1D (0.44) | SPHK2ADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL29766272 | 0.80 | ADRA1D (0.44) | SPHK2ADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL14378591 | 0.78 | PPARD (0.67) | — | |
| SCHEMBL9491587 | 0.78 | TAOK1 (0.53) | ADRA1DADRA1AADRA1BTAOK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |