Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | HPD | P32754 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490891 | 0.88 | ALDH1A1 (0.50) | SPHK2SCN3ANPC1RAB9AALDH1A1 | |
| SCHEMBL9487573 | 0.88 | TAOK1 (0.53) | MAOBMAOASCN3ANPC1RAB9A | |
| SCHEMBL9492340 | 0.84 | GAA (0.48) | MAOBSCN3AALDH1A1MAPT | |
| SCHEMBL9488534 | 0.81 | SMPD1 (0.48) | MAOBMAOASPHK2SCN3ANPC1 | |
| SCHEMBL9488808 | 0.80 | LIPG (0.57) | MAOBMAOASCN3AMAPTMMP2 | |
| SCHEMBL9491587 | 0.78 | TAOK1 (0.53) | MAOBMAOA | |
| SCHEMBL9492132 | 0.77 | HRH3 (0.47) | SCN3ANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9492388 | 0.76 | MAOA (0.49) | MAOBMAOANPC1RAB9AALDH1A1 | |
| SCHEMBL9490515 | 0.75 | TAS1R3 (0.56) | MAOBMAOAALDH1A1MAPTTAS1R3 | |
| SCHEMBL9490780 | 0.73 | CYSLTR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |