Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491040 | 0.86 | MAPT (0.53) | L3MBTL1KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL9490689 | 0.84 | MMP2 (0.54) | KMT2APOLBMEN1ALDH1A1TSHR | |
| SCHEMBL9490572 | 0.80 | MMP2 (0.55) | KMT2APOLBMEN1ALDH1A1TSHR | |
| SCHEMBL9490595 | 0.79 | CTSG (0.44) | L3MBTL1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL9490445 | 0.74 | MMP2 (0.54) | L3MBTL1KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL9490432 | 0.74 | MMP2 (0.54) | L3MBTL1KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL9489398 | 0.72 | MMP2 (0.56) | POLBALDH1A1MAPTPKMLMNA | |
| SCHEMBL9489643 | 0.71 | MEN1 (0.73) | L3MBTL1KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL10458998 | 0.70 | NPSR1 (0.49) | KMT2APOLBMEN1ALDH1A1TSHR | |
| SCHEMBL10461110 | 0.67 | NPSR1 (0.51) | KMT2AMEN1ALDH1A1MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940708-A | 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |