Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | DHODH | Q02127 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636690 | 0.87 | LMNA (0.78) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL28282946 | 0.84 | LMNA (0.73) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL2410062 | 0.84 | LMNA (0.72) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL2713370 | 0.84 | LMNA (0.72) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL5083062 | 0.83 | RAB9A (0.72) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL5255345 | 0.83 | LMNA (0.71) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL29898238 | 0.83 | LMNA (0.71) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL28949487 | 0.83 | LMNA (0.71) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL28309786 | 0.83 | LMNA (0.71) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL22492826 | 0.83 | LMNA (0.70) | LMNAMAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |