Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493952 | 0.90 | ALDH1A1 (0.33) | POLBALDH1A1TDP1 | |
| SCHEMBL9495007 | 0.80 | — | — | |
| SCHEMBL9496610 | 0.77 | MAPT (0.47) | MEN1KMT2ATSHRALDH1A1TDP1 | |
| SCHEMBL9495474 | 0.76 | RAB9A (0.40) | POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9499264 | 0.74 | TSHR (0.35) | POLBMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL9493946 | 0.68 | LMNA (0.34) | POLBMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL10969677 | 0.66 | KMT2A (0.47) | POLBMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL2381586 | 0.64 | TSHR (0.54) | POLBMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL9494505 | 0.62 | KMT2A (0.46) | POLBMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL3192684 | 0.61 | ALDH1A1 (0.62) | MEN1KMT2ATSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |