Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499268 | 0.90 | POLB (0.32) | ALDH1A1TDP1POLB | |
| SCHEMBL9494676 | 0.79 | CISD2 (0.31) | KDM4E | |
| SCHEMBL5252940 | 0.78 | RAB9A (0.44) | ALDH1A1LMNAATMSMN1; SMN2TDP1 | |
| SCHEMBL9493946 | 0.74 | LMNA (0.34) | ALDH1A1LMNAATMSMN1; SMN2TDP1 | |
| SCHEMBL9499264 | 0.68 | TSHR (0.35) | ALDH1A1LMNASMN1; SMN2TDP1POLB | |
| SCHEMBL9496610 | 0.67 | MAPT (0.47) | ALDH1A1LMNAATMSMN1; SMN2TDP1 | |
| SCHEMBL10969677 | 0.65 | KMT2A (0.47) | ALDH1A1LMNASMN1; SMN2TDP1POLB | |
| SCHEMBL9495474 | 0.65 | RAB9A (0.40) | ALDH1A1LMNAATMSMN1; SMN2POLB | |
| SCHEMBL3347421 | 0.65 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TDP1POLBKDM4E | |
| SCHEMBL9494442 | 0.63 | NPC1 (0.40) | ALDH1A1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |