Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498545 | 0.87 | ALDH1A1 (0.54) | UTS2RALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL9500077 | 0.86 | ALDH1A1 (0.55) | UTS2RALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9499271 | 0.86 | NPSR1 (0.53) | UTS2RALDH1A1TDP1POLBMEN1 | |
| SCHEMBL9500258 | 0.84 | CYP2A6 (0.53) | UTS2RALDH1A1TDP1POLBMEN1 | |
| SCHEMBL22416005 | 0.82 | PDCD1 (0.53) | UTS2RALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9498981 | 0.82 | PDCD1 (0.53) | UTS2RALDH1A1POLBMEN1KMT2A | |
| SCHEMBL803259 | 0.82 | PDCD1 (0.53) | UTS2RALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9502047 | 0.82 | RARB (0.53) | UTS2RALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9501806 | 0.82 | THRA (0.49) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL9499364 | 0.81 | L3MBTL1 (0.39) | UTS2RALDH1A1TDP1POLBCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |