Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 4/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496291 | 0.80 | HSPB1 (0.39) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL9497883 | 0.78 | ALDH1A1 (0.54) | MAOAMAOBHPGDMEN1KMT2A | |
| SCHEMBL9496376 | 0.78 | CA1 (0.48) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL9497570 | 0.78 | MEN1 (0.54) | HPGDMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9498019 | 0.78 | TEAD4 (0.45) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9498280 | 0.78 | MAPT (0.45) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL9364922 | 0.77 | LTA4H (0.50) | MAOAMAOBKMT2AKDM4EMAPT | |
| SCHEMBL9366572 | 0.75 | PARP10 (0.38) | HPGDKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9496753 | 0.74 | PARP15 (0.43) | MAOBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9775401 | 0.74 | IDO1 (0.45) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343441-B1 | FLUORINATED BIS-ARYLOXY-SUBSTITUTED ALKENES, METHOD FOR THEIR PRODUCTION AN THEIR APPLICATION | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-4990633-A | Used as insulating agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |