SCHEMBL9775401

SCHEMBL9775401

FC1(F)C(Oc2ccc(CS)cc2)=C(Oc2ccc(CS)cc2)C(F)(F)C1(F)F

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.45
ST14 Q9Y5Y6 1/20 0.31
LTA4H P09960 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285383 0.76 IDO1 (0.64) IDO1ST14LTA4H
SCHEMBL9496291 0.75 HSPB1 (0.39) LTA4H
SCHEMBL15788328 0.74 SRD5A2 (0.34) LTA4H
SCHEMBL9497570 0.74 MEN1 (0.54) LTA4H
SCHEMBL9498019 0.74 TEAD4 (0.45)
SCHEMBL9500512 0.74 MAOA (0.45) LTA4H
SCHEMBL9497883 0.74 ALDH1A1 (0.54)
SCHEMBL9498280 0.74 MAPT (0.45) LTA4H
SCHEMBL9497007 0.73 ESR1 (0.46)
SCHEMBL9364922 0.73 LTA4H (0.50) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990633-A Used as insulating agents BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed