Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323154 | 0.71 | KMT2A (0.49) | ALDH1A1MRGPRX1HTTKMT2AMEN1 | |
| SCHEMBL9321851 | 0.71 | KMT2A (0.55) | ALDH1A1SMN1; SMN2HTTKMT2AGAA | |
| SCHEMBL1122639 | 0.69 | PTK2B (0.49) | PSIP1PTGS2ALDH1A1SMN1; SMN2CXCL8 | |
| SCHEMBL11405281 | 0.69 | RAB9A (0.36) | SLC22A12PTGS2ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1122648 | 0.69 | KMT2A (0.49) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6054954 | 0.69 | RAB9A (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL9321059 | 0.69 | SLC22A12 (0.53) | SLC22A12 | |
| SCHEMBL8912616 | 0.67 | ALDH1A1 (0.37) | PTGS2ALDH1A1CXCL8HTTKMT2A | |
| SCHEMBL29950893 | 0.66 | PSIP1 (0.42) | PSIP1ALDH1A1SMN1; SMN2GAALIMK2 | |
| SCHEMBL7264830 | 0.66 | ALDH1A1 (0.51) | ALDH1A1HTTKMT2AMEN1LIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |