Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502196 | 0.89 | CYP2D6 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ACYP2D6 | |
| SCHEMBL9504119 | 0.86 | CYP2D6 (0.44) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9502157 | 0.82 | GPBAR1 (0.47) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9502829 | 0.82 | SIGMAR1 (0.41) | ALDH1A1SMN1; SMN2POLBKDM4E | |
| SCHEMBL10518201 | 0.78 | CXCR4 (0.46) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9502751 | 0.68 | KDM4E (0.39) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1029651 | 0.67 | RECQL (0.73) | TSHRALDH1A1RECQLSMN1; SMN2MEN1 | |
| SCHEMBL10386225 | 0.67 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MEN1KMT2ACYP2D6 | |
| SCHEMBL9502634 | 0.65 | LMNA (0.49) | TSHRALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL27565870 | 0.65 | KMT2A (0.61) | TSHRALDH1A1RECQLSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | claimed |
| EP-0330910-A1 | Propane derivatives | KOWA COMPANY, LTD. (JP) | 1989-09-06 | — | — | EP | claimed |