Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504119 | 0.96 | CYP2D6 (0.44) | CYP2D6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9502763 | 0.89 | FABP6 (0.43) | CYP2D6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9502157 | 0.88 | GPBAR1 (0.47) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9502829 | 0.80 | SIGMAR1 (0.41) | ALDH1A1POLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL10386225 | 0.78 | ALDH1A1 (0.45) | CYP2D6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL10518201 | 0.77 | CXCR4 (0.46) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9502634 | 0.76 | LMNA (0.49) | CYP2D6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL12726868 | 0.75 | CYP2D6 (0.76) | CYP2D6KMT2AALDH1A1POLBLMNA | |
| SCHEMBL9501073 | 0.72 | GAA (0.59) | CYP2D6KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9502176 | 0.71 | KDM4E (0.48) | CYP2D6KMT2AALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | claimed |
| US-4960883-A | Cardiovascular disorders | KOWA COMPANY, LTD. (JP) | 1990-10-02 | — | — | US | claimed |
| EP-0330910-A1 | Propane derivatives | KOWA COMPANY, LTD. (JP) | 1989-09-06 | — | — | EP | claimed |