Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504013 | 0.78 | KDM4E (0.40) | KDM4EKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL9502833 | 0.76 | SLC6A4 (0.44) | KDM4EKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL9502192 | 0.74 | TDP1 (0.43) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9502149 | 0.71 | TSHR (0.48) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9501166 | 0.69 | ALDH1A1 (0.40) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9501464 | 0.66 | BCHE (0.38) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10516652 | 0.62 | ALDH1A1 (0.38) | KDM4EALDH1A1LMNATDP1NPC1 | |
| SCHEMBL18195122 | 0.60 | KMT2A (0.54) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8635727 | 0.60 | CHRM2 (0.54) | KDM4EALDH1A1LMNAHTT | |
| SCHEMBL8957307 | 0.59 | TAAR1 (0.46) | KDM4EKMT2AMEN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | claimed |