Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504013 | 0.89 | KDM4E (0.40) | TDP1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL9502149 | 0.88 | TSHR (0.48) | KDM4EKMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL9502833 | 0.81 | SLC6A4 (0.44) | KDM4EKMT2ALMNAMEN1CYP2D6 | |
| SCHEMBL9502176 | 0.80 | KDM4E (0.48) | TDP1KDM4EKMT2ALMNAMCOLN3 | |
| SCHEMBL9504097 | 0.77 | KDM4E (0.45) | TDP1KDM4EKMT2ALMNAMCOLN3 | |
| SCHEMBL9501470 | 0.74 | KDM4E (0.38) | TDP1KDM4EKMT2ALMNAALDH1A1 | |
| SCHEMBL10386225 | 0.71 | ALDH1A1 (0.45) | KDM4EKMT2ALMNAALDH1A1GAA | |
| SCHEMBL9501107 | 0.69 | TSHR (0.48) | TDP1KDM4EKMT2ALMNAALDH1A1 | |
| SCHEMBL9502751 | 0.68 | KDM4E (0.39) | TDP1KDM4EKMT2ALMNAALDH1A1 | |
| SCHEMBL9501073 | 0.67 | GAA (0.59) | KMT2ALMNAALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | claimed |