Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502192 | 0.89 | TDP1 (0.43) | KDM4EKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL9502833 | 0.83 | SLC6A4 (0.44) | KDM4EKMT2AMEN1CYP2D6 | |
| SCHEMBL9502149 | 0.83 | TSHR (0.48) | KDM4EKMT2AMEN1NPSR1TSHR | |
| SCHEMBL9502751 | 0.78 | KDM4E (0.39) | KDM4EKMT2AMEN1NPSR1TSHR | |
| SCHEMBL9501470 | 0.78 | KDM4E (0.38) | KDM4EKMT2AMEN1NPSR1TSHR | |
| SCHEMBL9502176 | 0.68 | KDM4E (0.48) | KDM4EKMT2AALDH1A1TDP1POLB | |
| SCHEMBL8635727 | 0.66 | CHRM2 (0.54) | KDM4EALDH1A1HTT | |
| SCHEMBL9504097 | 0.66 | KDM4E (0.45) | KDM4EKMT2ATSHRALDH1A1TDP1 | |
| SCHEMBL9502822 | 0.62 | LMNA (0.50) | KDM4EKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL8750527 | 0.60 | TACR1 (0.42) | KDM4ETSHRALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | claimed |
| EP-0330910-A1 | Propane derivatives | KOWA COMPANY, LTD. (JP) | 1989-09-06 | — | — | EP | claimed |