Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 6/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | PPM1D | O15297 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501952 | 0.81 | CYP19A1 (0.68) | CYP19A1PTGS1PTGS2MEN1PTGES | |
| SCHEMBL17553872 | 0.78 | PTGS1 (0.39) | CYP19A1PTGS1MAPTPLA2G7ADRB3 | |
| SCHEMBL20963038 | 0.75 | CEL (0.43) | CYP19A1KMT2A | |
| SCHEMBL23579165 | 0.73 | NFE2L2 (0.41) | CYP19A1ALDH1A1MAPTSMN1; SMN2PPM1D | |
| SCHEMBL29973214 | 0.73 | NFE2L2 (0.41) | CYP19A1ALDH1A1MAPTSMN1; SMN2PPM1D | |
| SCHEMBL2310180 | 0.71 | PTGS1 (0.42) | PTGS1PTGS2MAPTPLA2G7ADRB3 | |
| SCHEMBL3244812 | 0.70 | L3MBTL1 (0.42) | PTGS1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL14799138 | 0.70 | CYP19A1 (0.59) | CYP19A1PTGS1PTGS2MEN1PTGES | |
| SCHEMBL8979023 | 0.70 | PTGS2 (0.57) | CYP19A1PTGS1PTGS2MEN1PTGES | |
| SCHEMBL10012239 | 0.70 | CEL (0.42) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317332-B1 | SULFONANILIDE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4885367-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECT REDUCTION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0317332-A2 | Sulfonanilide compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1989-05-24 | — | — | EP | disclosed |