Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 5/20 | 0.40 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502675 | 0.87 | CA2 (0.51) | ALDH1A1CA2CA7MMP2MMP9 | |
| SCHEMBL9299658 | 0.86 | DUT (0.48) | ALDH1A1ATML3MBTL1CA2CA7 | |
| SCHEMBL9501062 | 0.80 | GBA1 (0.44) | ALDH1A1ATML3MBTL1MAPT | |
| SCHEMBL9502208 | 0.80 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1CA2MMP2MMP9 | |
| SCHEMBL9502025 | 0.79 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CA2MMP2MMP9 | |
| SCHEMBL9503647 | 0.78 | LMNA (0.48) | ALDH1A1CA2MAPT | |
| SCHEMBL30801085 | 0.78 | CA2 (0.63) | ALDH1A1ATML3MBTL1S1PR1CA2 | |
| SCHEMBL16300320 | 0.78 | CA2 (0.63) | ALDH1A1ATML3MBTL1S1PR1CA2 | |
| SCHEMBL8566023 | 0.76 | ALDH1A1 (0.53) | ALDH1A1ATML3MBTL1S1PR1CA2 | |
| SCHEMBL8134454 | 0.75 | GAA (0.47) | MMP2MMP9ADAMTS4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003422-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | claimed |
| EP-0543861-A1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| US-5180723-A | Hypertensives, bronchodilators, antiedemic agents | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-01-19 | — | — | US | disclosed |
| WO-1992003422-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |