Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 8/20 | 0.42 |
| ▸ | MMP9 | P14780 | 7/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMTK3 | Q96Q04 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501945 | 0.87 | ALDH1A1 (0.47) | CA2CA7MMP2MMP9ADAMTS4 | |
| SCHEMBL9299658 | 0.84 | DUT (0.48) | CA2CA7MMP2MMP9ALDH1A1 | |
| SCHEMBL9502208 | 0.82 | ALDH1A1 (0.64) | CA2CA9MMP2MMP9ALDH1A1 | |
| SCHEMBL9502025 | 0.80 | ALDH1A1 (0.47) | CA2CA9MMP2MMP9ALDH1A1 | |
| SCHEMBL9501062 | 0.78 | GBA1 (0.44) | CA9ALDH1A1MAPTKMT2ACYP1A2 | |
| SCHEMBL8134454 | 0.78 | GAA (0.47) | MMP2MMP9ADAMTS4MAPTMMP7 | |
| SCHEMBL8560865 | 0.77 | SMN1; SMN2 (0.49) | CA2CA9MMP2MMP9ALDH1A1 | |
| SCHEMBL8137542 | 0.77 | MMP1 (0.55) | MMP2MMP9ALDH1A1MAPTKMT2A | |
| SCHEMBL8134055 | 0.76 | MMP2 (0.43) | MMP2MMP9ADAMTS4CTSLCTSS | |
| SCHEMBL9673430 | 0.75 | SMN1; SMN2 (0.52) | ALDH1A1KMT2APOLBCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543861-A1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-06-02 | — | — | EP | claimed |
| WO-1992003422-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | claimed |
| EP-0543861-A1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| US-5180723-A | Hypertensives, bronchodilators, antiedemic agents | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-01-19 | — | — | US | disclosed |
| WO-1992003422-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |