Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 10/20 | 0.50 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | PGK2 | P07205 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999640 | 0.84 | ESR1 (0.52) | PGK1PGK2 | |
| SCHEMBL11759829 | 0.84 | TSHR (0.48) | PTPN5PGK1PGK2PTPN1PTPN2 | |
| SCHEMBL17923871 | 0.82 | PGK1 (0.46) | PTPN5PGK1PGK2PTPN1PTPN2 | |
| SCHEMBL2637396 | 0.82 | FDPS (0.47) | PTPN5PGK1PGK2PTPN1PTPN2 | |
| SCHEMBL1099732 | 0.81 | PTPN1 (0.58) | PTPN5PGK1PGK2PTPN1 | |
| SCHEMBL6766182 | 0.77 | PGK1 (0.37) | PTPN5PGK1PGK2PTPN1PTPN2 | |
| SCHEMBL11760465 | 0.77 | PTPN1 (0.57) | PGK1PGK2PTPN1PTPN2PTPN6 | |
| SCHEMBL9017748 | 0.77 | ENPP2 (0.47) | PGK1PGK2PTPN1KIF11 | |
| SCHEMBL17008450 | 0.77 | ALDH1A1 (0.42) | PTPN5PGK1PGK2PTPN1PTPN2 | |
| SCHEMBL5718106 | 0.77 | PTPN5 (0.57) | PTPN5PGK1PGK2PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298361-B1 | LIQUID DETERGENE CONTAINING DISULFONATED OPTICAL BRIGHTENERS | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-4925595-A | STORAGE STABLE DETERGENT | CIBA-GEIGY CORPORATION (US) | 1990-05-15 | — | — | US | disclosed |
| US-4147648-A | Brightening compositions | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-4118560-A | Substituted 1,4-bis-styrylbenzene and 4,4'-bis styrylbiphenyl and their use as optical brightners | CIBA-GEIGY CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |