Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.57 |
| ▸ | PGK1 | P00558 | 3/20 | 0.41 |
| ▸ | PGK2 | P07205 | 3/20 | 0.41 |
| ▸ | PTPRC | P08575 | 3/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | EPM2A | O95278 | 1/20 | 0.39 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398056 | 0.92 | PTPN1 (0.66) | PTPN1PGK1PGK2PTPRC | |
| SCHEMBL11760714 | 0.91 | PTPN1 (0.49) | PTPN1PGK1PGK2PTPRCPTPN6 | |
| SCHEMBL11032045 | 0.79 | ENPP2 (0.52) | PTPN1PTPN6PTPN11KDM4EPTPN2 | |
| SCHEMBL11028547 | 0.79 | ENPP2 (0.52) | PTPN1PTPN6PTPN11KDM4EPTPN2 | |
| SCHEMBL9502470 | 0.77 | PTPN5 (0.50) | PTPN1PGK1PGK2PTPN6PTPN11 | |
| SCHEMBL11756580 | 0.77 | LMNA (0.38) | PTPN1KDM4E | |
| SCHEMBL11759829 | 0.76 | TSHR (0.48) | PTPN1PGK1PGK2PTPN6PTPN11 | |
| SCHEMBL8999640 | 0.76 | ESR1 (0.52) | PGK1PGK2KDM4EMEN1KMT2A | |
| SCHEMBL2637396 | 0.74 | FDPS (0.47) | PTPN1PGK1PGK2PTPN6PTPN11 | |
| SCHEMBL17923871 | 0.74 | PGK1 (0.46) | PTPN1PGK1PGK2PTPN6PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061681-A | Method for the preparation of mono- or poly [dialkyl or dicycloalkylphosphonylmethyl] aromatic carbocyclic compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |