Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | KLK7 | P49862 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | PPID | Q08752 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162007 | 0.83 | PKM (0.62) | PKMKLK7KMT2AMEN1LMNA | |
| SCHEMBL4158526 | 0.83 | PKM (0.62) | PKMKLK7KMT2AMEN1LMNA | |
| SCHEMBL4158522 | 0.83 | PKM (0.62) | PKMKLK7KMT2AMEN1LMNA | |
| SCHEMBL11791194 | 0.81 | PPARA (0.49) | KMT2AMEN1LMNAALDH1A1GAA | |
| SCHEMBL9503442 | 0.79 | CYP2D6 (0.66) | PKMKLK7KMT2AMEN1LMNA | |
| SCHEMBL10692649 | 0.78 | PKM (0.76) | PKMKLK7KMT2AMEN1LMNA | |
| SCHEMBL18134893 | 0.78 | PKM (0.67) | PKMKLK7KMT2AMEN1CA12 | |
| SCHEMBL11815432 | 0.77 | MMP8 (0.45) | KMT2AMEN1ALDH1A1GAAMMP8 | |
| SCHEMBL14776377 | 0.77 | PPID (0.57) | PKMKMT2AMEN1PPIDCA12 | |
| SCHEMBL257848 | 0.76 | PKM (0.71) | PKMKLK7KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376852-B1 | MICROGRANULES ESSENTIALLY CONSISTING OF TRIGLYCERIDES OF SATURATED FATTY ACIDS LOADED WITH AN ACTIVE SUBSTANCE, AND THEIR TOPICAL THERAPEUTICAL USE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-06-23 | — | — | EP | claimed |