Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30115835 | 0.80 | MGLL (0.68) | NPSR1POLBMITFALDH1A1HTT | |
| SCHEMBL2636652 | 0.80 | NPSR1 (0.61) | NPSR1POLBMITFALDH1A1HTT | |
| SCHEMBL4577008 | 0.79 | NPSR1 (0.54) | NPSR1POLBMITFALDH1A1HTT | |
| SCHEMBL11802189 | 0.79 | ALDH1A1 (0.67) | NPSR1POLBMITFALDH1A1HTT | |
| SCHEMBL4003071 | 0.78 | MAPT (0.66) | NPSR1POLBMITFALDH1A1HTT | |
| SCHEMBL28041453 | 0.78 | NPSR1 (0.59) | NPSR1POLBMITFALDH1A1HTT | |
| SCHEMBL4007324 | 0.77 | NPSR1 (0.66) | NPSR1POLBMITFALDH1A1HTT | |
| SCHEMBL30802615 | 0.77 | PARP1 (0.69) | NPSR1POLBMITFALDH1A1HTT | |
| SCHEMBL29200312 | 0.77 | PARP1 (0.69) | NPSR1POLBMITFALDH1A1HTT | |
| SCHEMBL30675594 | 0.76 | NLRP3 (0.62) | NPSR1POLBMITFALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550574-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992005180-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |