Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.43 |
| ▸ | TUBB | P07437 | 5/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501058 | 0.94 | GPR84 (0.41) | CTSVCTSLTUBB4ATUBBTUBA3C | |
| SCHEMBL9452266 | 0.82 | KDM4E (0.56) | CTSVCTSLLMNACYP1A2ALDH1A1 | |
| SCHEMBL9452299 | 0.78 | KDM4E (0.46) | CTSVCTSLTUBB4ATUBBTUBA3C | |
| SCHEMBL9502884 | 0.75 | EIF4A3 (0.50) | LMNAHPGD | |
| SCHEMBL18611883 | 0.74 | KIF11 (0.55) | CTSVCTSLTUBB4ATUBBTUBA3C | |
| SCHEMBL9502885 | 0.73 | PDE2A (0.42) | CTSVCTSLALDH1A1HPGDHSD17B10 | |
| SCHEMBL10809192 | 0.73 | KDM4E (0.58) | CTSVCTSLTUBB4ATUBBTUBA3C | |
| SCHEMBL9452205 | 0.73 | KDM4E (0.58) | LMNACYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9499282 | 0.72 | CCNB2 (0.38) | LMNACYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11260822 | 0.71 | ALDH1A1 (0.36) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303387-B1 | KYNURENIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS | MERCK SHARP & DOHME LTD. (GB) | 1993-04-21 | — | — | EP | claimed |