Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408444 | 0.78 | LMNA (0.59) | LMNAP2RX7ALDH1A1KMT2AGRM2 | |
| SCHEMBL2163180 | 0.78 | LMNA (0.59) | LMNAP2RX7ALDH1A1KMT2AGRM2 | |
| SCHEMBL31272600 | 0.78 | POLB (0.42) | LMNAP2RX7ALDH1A1KMT2AGRM2 | |
| SCHEMBL7433479 | 0.78 | ALDH1A1 (0.53) | LMNAALDH1A1TSHR | |
| SCHEMBL994214 | 0.77 | LMNA (0.57) | LMNAP2RX7ALDH1A1KMT2AGRM2 | |
| SCHEMBL4527137 | 0.77 | LMNA (0.57) | LMNAP2RX7ALDH1A1KMT2AGRM2 | |
| SCHEMBL3261613 | 0.77 | LMNA (0.57) | LMNAP2RX7ALDH1A1KMT2AGRM2 | |
| SCHEMBL3035928 | 0.77 | LMNA (0.62) | LMNAP2RX7ALDH1A1KMT2AGRM2 | |
| SCHEMBL1318724 | 0.77 | LMNA (0.57) | LMNAP2RX7ALDH1A1KMT2AGRM2 | |
| SCHEMBL27333607 | 0.77 | LMNA (0.57) | LMNAP2RX7ALDH1A1KMT2AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240276957-A1 | METHODS OF TREATMENT WITH AMINOLEVULINIC ACID SYNTHASE 2 (ALAS2) MODULATORS | AGIOS PHARMACEUTICALS, INC. | 2024-08-22 | — | — | US | disclosed |
| CN-110003271-B | Process for producing aromatic compound | 住友化学株式会社 | 2022-05-03 | — | — | CN | disclosed |
| CN-114174288-A | Methods of treatment with aminolevulinic acid synthase 2(ALAS2) modulators | 安吉奥斯医药品有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-11045796-B2 | Process for producing aromatic compound, and palladium complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-29 | — | — | US | disclosed |
| CN-108368142-B | Method for producing aromatic compound and palladium complex | 住友化学株式会社 | 2021-02-19 | — | — | CN | disclosed |
| WO-2020247819-A2 | METHODS OF TREATMENT WITH AMINOLEVULINIC ACID SYNTHASE 2 (ALAS2) MODULATORS | AGIOS PHARMACEUTICALS, INC. (US) | 2020-12-10 | — | — | WO | disclosed |
| US-20200369653-A1 | 5-(2,5-BIS(4-CHLORO-2-ISOPROPYLPHENYL)THIOPHEN-3-YL)-1H-TETRAZOLE FOR THE TOPICAL TREATMENT OF BACTERIAL INFECTIONS | DENOVAMED INC. (CA) | 2020-11-26 | — | — | US | disclosed |
| US-20180369799-A1 | PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-12-27 | — | — | US | disclosed |
| EP-3385270-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX | Sumitomo Chemical Company, Ltd (JP) | 2018-10-10 | — | — | EP | disclosed |
| US-9982087-B2 | Method for producing compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-29 | — | — | US | disclosed |
| WO-2011004017-A1 | 1-(6 MEMBERS AZO-HETEROCYCLIC)-PYRROLIN-2-ONE COMPOUNDS AS INHIBITORS OF HEPATITIS C NS5B POLYMERASE, THE PHARMACEUTICAL COMPOSITION THEREOF AND THEIR THERAPEUTIC USE | VIVALIS (FR) | 2011-01-13 | — | — | WO | disclosed |
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-20090306397-A1 | Method for the production of substituted azoles | LANXESS DEUTSCHLAND GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-1891025-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED AZOLES | Lanxess Deutschland GmbH (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006131228-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED AZOLES | LANXESS DEUTSCHLAND GMBH (DE) | 2006-12-14 | — | — | WO | disclosed |
| US-20060111593-A1 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-05-25 | — | — | US | disclosed |
| US-7041856-B2 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-05-09 | — | — | US | disclosed |
| US-20030162950-A1 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-08-28 | — | — | US | disclosed |
| EP-1306131-A2 | Cross-Coupling catalyst comprising a cyclic nitrogen ligand and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162950-A1 | Coupling catalyst and process using the same | NOD1, PYM1, C9 | LMNA 1888/4885P2RX7 1712/4885ALDH1A1 3293/4885 |
| US-11045796-B2 | Process for producing aromatic compound, and palladium complex | DDT, DRD1, DRD2 | LMNA 4732/4885P2RX7 1730/4885ALDH1A1 1822/4885 |
| US-20200369653-A1 | 5-(2,5-BIS(4-CHLORO-2-ISOPROPYLPHENYL)THIOPHEN-3-YL)-1H-TETRAZOLE FOR THE TOPICAL TREATMENT OF BACTERIAL INFECTIONS | TLR5, CUTA, IL5 | LMNA 4304/4885P2RX7 894/4885ALDH1A1 1300/4885 |
| US-20090306397-A1 | Method for the production of substituted azoles | CYP11B1, CYP11B2, CYP4F11 | LMNA 3460/4885P2RX7 3267/4885ALDH1A1 389/4885 |
| US-20060111593-A1 | Coupling catalyst and process using the same | RPL22, C9, RBM22 | LMNA 1071/4885P2RX7 332/4885ALDH1A1 3723/4885 |
| US-20180369799-A1 | PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX | DDT, DRD1, DRD2 | LMNA 4732/4885P2RX7 1730/4885ALDH1A1 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.