Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506078 | 0.81 | ALOX5 (0.63) | MEN1KMT2AHDAC1HDAC8ALOX5 | |
| SCHEMBL9506114 | 0.78 | MAOB (0.62) | MAOBLMNATOP1CA1CA2 | |
| SCHEMBL5020596 | 0.78 | MAOB (0.62) | MAOBLMNATOP1CA1CA2 | |
| SCHEMBL125680 | 0.78 | HSP90AA1 (0.54) | MEN1KMT2A | |
| SCHEMBL9504873 | 0.76 | GPR52 (0.48) | ALOX5MLYCD | |
| SCHEMBL9504867 | 0.76 | GPR52 (0.48) | ALOX5MLYCD | |
| SCHEMBL3282793 | 0.75 | HPGD (0.50) | MEN1KMT2AALOX5 | |
| SCHEMBL23169174 | 0.74 | MAPT (0.61) | — | |
| SCHEMBL3305633 | 0.74 | HPGD (0.62) | MEN1KMT2ALMNA | |
| SCHEMBL9877236 | 0.74 | CA1 (0.63) | MEN1KMT2ALMNAHDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | claimed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | claimed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | claimed |