Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | KDM6A | O15550 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KDM5C | P41229 | 1/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.52 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17621624 | 0.76 | BRD4 (0.41) | KDM4ECYP2C9KDM6AKDM4ACYP2C19 | |
| Hydrochloric Acid SCHEMBL30032118 | 0.74 | BRD4 (0.39) | KDM4ECYP2C9KDM6AKDM4ACYP2C19 | |
| SCHEMBL27302249 | 0.74 | KDM4E (0.39) | KDM4ECYP2C9KDM6AKDM4ACYP2C19 | |
| SCHEMBL15739595 | 0.74 | ALDH1A1 (0.36) | KDM4ECYP2C9KDM6AKDM4ACYP2C19 | |
| SCHEMBL15613418 | 0.74 | GABRA1 (0.46) | KDM4ECYP2C9KDM6AKDM4ACYP2C19 | |
| SCHEMBL24112194 | 0.73 | ATAD2 (0.40) | KDM4ECYP2C9KDM6AKDM4ACYP2C19 | |
| SCHEMBL21575044 | 0.73 | BRD4 (0.38) | KDM4ECYP2C9KDM6AKDM4ACYP2C19 | |
| SCHEMBL12033675 | 0.73 | KDM4E (0.47) | KDM4ECYP2C9KDM6AKDM4ACYP2C19 | |
| SCHEMBL21921079 | 0.73 | BRD4 (0.38) | KDM4ECYP2C9KDM6AKDM4ACYP2C19 | |
| SCHEMBL20516739 | 0.73 | BRD4 (0.38) | KDM4ECYP2C9KDM6AKDM4ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170340759-A1 | RADIO-PHARMACEUTICAL COMPLEXES | BAYER AS (NO) | 2017-11-30 | — | — | US | disclosed |
| US-20170183365-A1 | MACROCYCLES | LUMIPHORE, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9439984-B2 | Macrocycles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-09-13 | — | — | US | disclosed |
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| US-20150157746-A1 | MACROCYCLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-11 | — | — | US | disclosed |
| CN-100575345-C | 2 type Cannabined receptors are had in conjunction with active Pyridione derivatives | SHIONOGI & CO | 2009-12-30 | — | — | CN | disclosed |
| CN-1492856-A | Pyridone derivative having affinity for cannabinoid 2-type receptor | ��Ұ����ҩ��ʽ���� | 2004-04-28 | — | — | CN | disclosed |
| EP-0297397-B1 | PREPARATION OF DIAZO AND AZO COMPOUNDS | BAYER AG (DE) | 1993-08-04 | — | — | EP | disclosed |
| US-4942225-A | Preparation of diazo and azo compounds using azidoformamidium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0093306-B1 | METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS | BAYER AG (DE) | 1986-09-24 | — | — | EP | disclosed |
| EP-0093306-A1 | Methods for the preparation of azo compounds, and azo compounds | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221971-A1 | DI-MACROCYCLES | DLD, NDC1, MCL1 | KDM4E 4621/4885CYP2C9 1653/4885KDM6A 4857/4885 |
| US-20170183365-A1 | MACROCYCLES | HCCS, ABCB7, AURKAIP1 | KDM4E 4482/4885CYP2C9 1417/4885KDM6A 4757/4885 |
| US-20150157746-A1 | MACROCYCLES | SLC39A14, SLC39A3, SLC40A1 | KDM4E 2971/4885CYP2C9 2910/4885KDM6A 3608/4885 |
| US-20170340759-A1 | RADIO-PHARMACEUTICAL COMPLEXES | PTMS, THOP1, PHPT1 | KDM4E 4022/4885CYP2C9 3756/4885KDM6A 2267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.