Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503329 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1NPBWR1SMN1; SMN2MCHR1 | |
| SCHEMBL9505422 | 0.83 | BCHE (0.36) | KDM4E | |
| SCHEMBL9503554 | 0.79 | NPC1 (0.35) | KDM4ESMN1; SMN2 | |
| SCHEMBL9505418 | 0.73 | SIGMAR1 (0.43) | KDM4E | |
| SCHEMBL9503527 | 0.70 | BCHE (0.40) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9503326 | 0.64 | SIGMAR1 (0.45) | — | |
| SCHEMBL9505419 | 0.63 | NCEH1 (0.45) | — | |
| SCHEMBL9503683 | 0.63 | DRD2 (0.64) | KDM4EDRD2 | |
| Hydrochloric Acid SCHEMBL9507149 | 0.62 | DRD2 (0.63) | KDM4EDRD2 | |
| SCHEMBL9503551 | 0.61 | SIGMAR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321967-B1 | COMPOUNDS ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1993-07-28 | — | — | EP | disclosed |
| EP-0321967-A2 | Compounds active on the cardiovascular system | ZAMBON GROUP S.p.A. (IT) | 1989-06-28 | — | — | EP | disclosed |