SCHEMBL950545

SCHEMBL950545

Clc1cc(Cl)c(I)c(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TSHR P16473 7/20 0.50
HSD17B10 Q99714 5/20 0.50
CYP3A4 P08684 5/20 0.50
RECQL P46063 3/20 0.50
HPGD P15428 3/20 0.43
AHR P35869 2/20 0.43
TP53 P04637 3/20 0.42
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
ALOX15 P16050 2/20 0.38
ALOX12 P18054 2/20 0.38
MAPK1 P28482 2/20 0.38
CASP1 P29466 2/20 0.38
CASP7 P55210 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
SLC22A2 O15244 1/20 0.38
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1505303 0.85 RAPGEF4 (0.45) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL29363049 0.83 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL565244 0.83 TSHR (0.56) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL29768378 0.83 TSHR (0.56) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL6177214 0.83 TSHR (0.44) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL28901856 0.83 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL16180760 0.77 TTR (0.35) ALDH1A1TSHRCYP3A4AHRMAPK1
SCHEMBL29768451 0.77 ERN1 (0.40) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL1505978 0.77 ERN1 (0.40) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL1505192 0.77 ALDH1A1 (0.36) ALDH1A1TSHRHSD17B10CYP3A4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025202185-A1 PROCESS FOR THE FUNCTIONALIZATION OF AN AROMATIC OR HETEROAROMATIC AMINO COMPOUND STUDIENGESELLSCHAFT KOHLE GGMBH (DE) 2025-10-02 WO disclosed
EP-4624456-A1 PROCESS FOR THE DEAMINATIVE HALOGENATION OF AN AROMATIC OR HETEROAROMATIC AMINO COMPOUND Studiengesellschaft Kohle gGmbH (DE) 2025-10-01 EP disclosed
US-20230384496-A1 OPTICAL MEMBER FOR USE IN DISPLAY DEVICE AND DISPLAY DEVICE INCLUDING DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-11-30 US disclosed
US-11789307-B2 Colorant filter, backlight unit, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-10-17 US disclosed
US-11733435-B2 Polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
US-20230026009-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER, POLARIZING PLATE, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-01-26 US disclosed
US-20230012898-A1 LAMINATE, DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-01-19 US disclosed
CN-111499540-B Method for preparing 2,4,6-trichlorobenzonitrile by ammoxidation method, special catalyst and preparation method 中南民族大学 2022-09-27 CN disclosed
US-20220223825-A1 LAMINATE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-07-14 US disclosed
US-20220199912-A1 LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-06-23 US disclosed
EP-1127060-B8 HYDROBORONATION PROCESS COMMW SCIENT IND RES ORG (AU) 2005-01-05 EP disclosed
WO-2004085408-A1 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES MITSUBISHI PHARMA CORPORATION (JP) 2004-10-07 WO disclosed
US-20040133028-A1 Hydroboronation process COMMONWEALTH SCIENTIFIC 2004-07-08 US disclosed
US-6680401-B1 BORON COMPOUNDS SUCH AS 4-(METHOXYMETHYL)-1,3,2-DIOXABOROLANE, USED AS COUPLERS OR CHEMICAL INTERMEDIATES FOR DRUGS, PESTICIDES OR IN COMBINATORIAL CHEMISTRY COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-01-20 US disclosed
EP-1127060-A4 HYDROBORONATION PROCESS COMMW SCIENT IND RES ORG (AU) 2002-08-21 EP disclosed
EP-1127060-A1 HYDROBORONATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2001-08-29 EP disclosed
WO-2000027853-A1 HYDROBORONATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-05-18 WO disclosed
EP-0109606-B1 PROCESS FOR THE FORMYLATION OF ARYL HALIDES BAYER AG (DE) 1986-01-22 EP disclosed
US-4536344-A USING A PHOSPINE OR PHOSPHITE BAYER AKTIENGESELLSCHAFT (DE) 1985-08-20 US disclosed
EP-0109606-A1 Process for the formylation of aryl halides BAYER AG (DE) 1984-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040133028-A1 Hydroboronation process ALKBH3, HPD, HVCN1 ALDH1A1 994/4885TSHR 3604/4885HSD17B10 344/4885
US-20220199912-A1 LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME LAGE3, ASIC1, ALG3 ALDH1A1 4/4885TSHR 4520/4885HSD17B10 1786/4885
US-20230012898-A1 LAMINATE, DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE EPCAM, ICAM1, STRA6 ALDH1A1 201/4885TSHR 3470/4885HSD17B10 2796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.