Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507079 | 0.76 | ADRA2A (0.39) | TAS1R3TAS1R1TAS1R2DRD2DRD1 | |
| SCHEMBL9503511 | 0.74 | TAS1R3 (0.41) | TAS1R3TAS1R1TAS1R2KMT2ADRD2 | |
| SCHEMBL9504423 | 0.70 | NPC1 (0.38) | TAS1R3TAS1R1TAS1R2KDM4EALDH1A1 | |
| SCHEMBL9504418 | 0.70 | HTR6 (0.38) | TAS1R3TAS1R1TAS1R2HTR6 | |
| SCHEMBL9504432 | 0.69 | ADRA2A (0.44) | IGF1RALOX15KDM4EFYN | |
| Hydrochloric Acid SCHEMBL9503363 | 0.68 | ADRA2A (0.43) | IGF1RALOX15KDM4EFYN | |
| Succinic Acid SCHEMBL9505506 | 0.68 | ADRA2A (0.39) | TAS1R3TAS1R1TAS1R2ACHEKDM4E | |
| SCHEMBL9504640 | 0.67 | PTGER4 (0.37) | — | |
| SCHEMBL9504412 | 0.67 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2IGF1RALOX15 | |
| SCHEMBL9503722 | 0.66 | ADRA2A (0.43) | KDM4EDRD2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321968-B1 | COMPOUNDS ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1993-07-28 | — | — | EP | disclosed |
| US-5151414-A | Hypotensive agents | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1992-09-29 | — | — | US | disclosed |