Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504432 | 0.82 | ADRA2A (0.44) | KDM4E | |
| Hydrochloric Acid SCHEMBL9503363 | 0.81 | ADRA2A (0.43) | KDM4E | |
| Succinic Acid SCHEMBL9505506 | 0.80 | ADRA2A (0.39) | TAS1R3TAS1R1TAS1R2KMT2AKDM4E | |
| SCHEMBL9503722 | 0.79 | ADRA2A (0.43) | KDM4E | |
| SCHEMBL9503307 | 0.76 | ADRA2A (0.48) | KDM4E | |
| SCHEMBL9507191 | 0.70 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2KMT2AKDM4E | |
| SCHEMBL9504418 | 0.70 | HTR6 (0.38) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9503275 | 0.69 | FYN (0.58) | KMT2ALMNA | |
| SCHEMBL9506547 | 0.65 | DRD2 (0.54) | — | |
| SCHEMBL9504412 | 0.65 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321968-B1 | COMPOUNDS ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1993-07-28 | — | — | EP | disclosed |