Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507079 | 0.90 | ADRA2A (0.39) | TAS1R3TAS1R1TAS1R2ADRA2AADRA2B | |
| SCHEMBL9503481 | 0.84 | AGTR2 (0.40) | — | |
| SCHEMBL9504640 | 0.74 | PTGER4 (0.37) | — | |
| SCHEMBL9507191 | 0.74 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2DRD2KMT2A | |
| SCHEMBL9503507 | 0.70 | TAS1R3 (0.43) | TAS1R3TAS1R1TAS1R2ADRA2AADRA2B | |
| SCHEMBL9505387 | 0.69 | ADRA2A (0.60) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL9507138 | 0.68 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9503495 | 0.67 | TAS1R3 (0.43) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9503482 | 0.63 | DRD2 (0.53) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL9503472 | 0.62 | MTNR1A (0.48) | ADRA1DADRA1AADRA1BDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321968-B1 | COMPOUNDS ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1993-07-28 | — | — | EP | disclosed |