Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDE6D | O43924 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509591 | 0.78 | FFAR1 (0.39) | L3MBTL1EPHX1PDE6DKLK7FFAR1 | |
| SCHEMBL9511010 | 0.77 | IDO1 (0.42) | MEN1KMT2AKLK7 | |
| SCHEMBL9510871 | 0.77 | ALDH1A1 (0.40) | L3MBTL1EPHX1MAPTMEN1KMT2A | |
| SCHEMBL9509549 | 0.76 | KMT2A (0.43) | L3MBTL1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL8430514 | 0.73 | FFAR1 (0.53) | EPHX1MAPTMEN1KMT2APTGDR2 | |
| SCHEMBL5970893 | 0.72 | APP (0.47) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6290570 | 0.72 | RAB9A (0.67) | L3MBTL1EPHX1MAPTMEN1KMT2A | |
| SCHEMBL13402346 | 0.71 | HPGD (0.47) | L3MBTL1EPHX1MAPTMEN1KMT2A | |
| SCHEMBL9510979 | 0.71 | MMP1 (0.42) | L3MBTL1EPHX1MAPTMEN1KMT2A | |
| SCHEMBL9235272 | 0.71 | LTA4H (0.55) | MAPTMEN1KMT2AALDH1A1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358305-B1 | MERCAPTO-PHENYLALCANOYLAMINO ACID AMIDES, THEIR PREPARATION AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1993-08-25 | — | — | EP | disclosed |
| US-5124322-A | Antiarthritic agents | BEECHAM GROUP P.L.C. (GB) | 1992-06-23 | — | — | US | disclosed |
| EP-0358305-A1 | Mercapto-phenylalcanoylamino acid amides, their preparation and their use as collagenase inhibitors | BEECHAM GROUP PLC (GB) | 1990-03-14 | — | — | EP | disclosed |