Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509591 | 0.92 | FFAR1 (0.39) | IDO1MMP1KLK7 | |
| SCHEMBL9509582 | 0.90 | IDO1 (0.37) | IDO1MMP1MEN1KMT2AKLK7 | |
| SCHEMBL9509572 | 0.88 | IDO1 (0.40) | IDO1MMP1MEN1KMT2AKLK7 | |
| SCHEMBL9510871 | 0.80 | ALDH1A1 (0.40) | MMP1MEN1KMT2AABL1SRC | |
| SCHEMBL9507226 | 0.77 | L3MBTL1 (0.43) | MEN1KMT2AKLK7 | |
| SCHEMBL9510979 | 0.76 | MMP1 (0.42) | MMP1MEN1KMT2A | |
| SCHEMBL9509549 | 0.75 | KMT2A (0.43) | MEN1KMT2A | |
| SCHEMBL9507453 | 0.75 | IDO1 (0.45) | IDO1MEN1KMT2A | |
| SCHEMBL9509583 | 0.72 | SLC6A4 (0.44) | IDO1MEN1KMT2A | |
| SCHEMBL9507230 | 0.70 | CTSB (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358305-B1 | MERCAPTO-PHENYLALCANOYLAMINO ACID AMIDES, THEIR PREPARATION AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1993-08-25 | — | — | EP | disclosed |
| US-5124322-A | Antiarthritic agents | BEECHAM GROUP P.L.C. (GB) | 1992-06-23 | — | — | US | disclosed |
| EP-0358305-A1 | Mercapto-phenylalcanoylamino acid amides, their preparation and their use as collagenase inhibitors | BEECHAM GROUP PLC (GB) | 1990-03-14 | — | — | EP | disclosed |