Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507230 | 0.81 | CTSB (0.40) | KMT2AL3MBTL1MEN1HTTSMN1; SMN2 | |
| SCHEMBL6158106 | 0.79 | SMN1; SMN2 (0.48) | KMT2AL3MBTL1MEN1SMN1; SMN2GAA | |
| SCHEMBL9509591 | 0.78 | FFAR1 (0.39) | L3MBTL1GAACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9507226 | 0.76 | L3MBTL1 (0.43) | KMT2AL3MBTL1MEN1HTTSMN1; SMN2 | |
| SCHEMBL9511010 | 0.75 | IDO1 (0.42) | KMT2AMEN1 | |
| SCHEMBL9510871 | 0.73 | ALDH1A1 (0.40) | KMT2AL3MBTL1MEN1SMN1; SMN2GAA | |
| SCHEMBL9510979 | 0.71 | MMP1 (0.42) | KMT2AL3MBTL1MEN1HTTGAA | |
| SCHEMBL6638095 | 0.70 | POLB (0.59) | KMT2AL3MBTL1POLBPTPRCMEN1 | |
| SCHEMBL8631418 | 0.70 | POLB (0.53) | KMT2AL3MBTL1POLBPTPRCMEN1 | |
| SCHEMBL9508519 | 0.69 | SMN1; SMN2 (0.41) | KMT2AL3MBTL1POLBMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358305-B1 | MERCAPTO-PHENYLALCANOYLAMINO ACID AMIDES, THEIR PREPARATION AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1993-08-25 | — | — | EP | disclosed |
| US-5124322-A | Antiarthritic agents | BEECHAM GROUP P.L.C. (GB) | 1992-06-23 | — | — | US | disclosed |
| EP-0358305-A1 | Mercapto-phenylalcanoylamino acid amides, their preparation and their use as collagenase inhibitors | BEECHAM GROUP PLC (GB) | 1990-03-14 | — | — | EP | disclosed |