Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 7/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139273 | 0.80 | PGR (0.49) | MEN1KMT2ATSHRHTR6ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28968464 | 0.79 | PGR (0.48) | MEN1KMT2ATSHRHTR6ALDH1A1 | |
| SCHEMBL8928012 | 0.78 | CA2 (0.48) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8928011 | 0.77 | TSHR (0.40) | TSHRHTR6ALDH1A1 | |
| SCHEMBL8919664 | 0.72 | POLB (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8960993 | 0.72 | CHAT (0.39) | MEN1KMT2ATSHRPGR | |
| SCHEMBL28753722 | 0.71 | KEAP1 (0.49) | MEN1KMT2ATSHRHTR6ALDH1A1 | |
| SCHEMBL8928013 | 0.71 | MAPT (0.40) | MEN1KMT2AHTR6ALDH1A1TP53 | |
| SCHEMBL22187492 | 0.70 | CA2 (0.63) | PGRRAB9A | |
| SCHEMBL28173820 | 0.70 | F2 (0.52) | TSHRHTR6ALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557383-A1 | METHOD OF INHIBITING TRANSFORMATION, GROWTH AND METASTASIS OF CELLS IN WHICH PURINE METABOLIC ENZYME ACTIVITY IS ELEVATED | AMIRA, INC. (US) | 1993-09-01 | — | — | EP | disclosed |