Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511404 | 0.86 | KDM4E (0.38) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL10641102 | 0.82 | ALDH1A1 (0.54) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11051768 | 0.77 | KMT2A (0.36) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1095842 | 0.74 | ALOX5 (0.39) | KDM4EALDH1A1MAPK1NPSR1HPGD | |
| SCHEMBL2524404 | 0.74 | ALOX5 (0.39) | KDM4EALDH1A1MAPK1NPSR1HPGD | |
| SCHEMBL11125145 | 0.74 | KMT2A (0.39) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL5185602 | 0.72 | CASP3 (0.35) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6561059 | 0.70 | HTT (0.39) | KDM4EALDH1A1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL10893856 | 0.70 | KMT2A (0.47) | KDM4EKMT2AMEN1MAPTHPGD | |
| SCHEMBL5187008 | 0.70 | KMT2A (0.41) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4390609-A | Electrophotographic recording material with abrasion resistant overcoat | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-06-28 | — | — | US | disclosed |